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Clinical trials database

Clinical trials in the NAPWHA database are listed below - the most recently-added entries are shown at the top of the list. Click the trial name for more information about that trial.

Rapid Testing

Clinical trial • Fully enrolled • 24 March 2011

Do homosexual men test more frequently for human immunodeficiency virus (HIV) with rapid tests? A randomised controlled trial.

Single

Clinical trial • No longer enrolling • 14 March 2011

A Randomized, Double-Blind Study of the Safety and Efficacy of GSK1349572 Plus Abacavir/Lamivudine Fixed-Dose Combination Therapy Administered Once Daily Compared to Atripla Over 96 Weeks in HIV-1 Infected Antiretroviral Therapy Naive Adult Subjects

SPRING 2

Clinical trial • No longer enrolling • 3 November 2010

This is a Randomized, Double Blind Study to look at the Safety and Efficacy of a novel Integrase Inhibitor (II) Dolutegravir at a dosage of 50mg taken once a day compared with Raltegravir 400mg taken twice a day. Both 'arms' are Administered With Fixed-dose Dual Nucleoside Reverse Transcriptase Inhibitor (NRTI) Therapy Over 96 Weeks among people with HIV who have not previously taken Antiretroviral Therapy.

SAILING

Clinical trial • No longer enrolling • 3 November 2010

A Randomized, Double-blind Study of the Safety and Efficacy of GSK1349572 50 mg Once Daily Versus Raltegravir 400 mg Twice Daily, Both Administered With an Investigator-selected Background Regimen Over 48 Weeks in HIV-1 Infected, Integrase Inhibitor-Naïve, Antiretroviral-Experienced Adults

'Booster' study

Clinical trial • No longer enrolling • 3 August 2010

Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of GS-9350-boosted Atazanavir Versus Ritonavir-boosted Atazanavir Each Administered With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults

QUAD

Clinical trial • No longer enrolling • 21 May 2010

A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Elvitegravir/Emtricitabine/Tenofovir Disoproxil Fumarate/GS-9350 Versus Ritonavir-Boosted Atazanavir Plus Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults

Pharmacist prescribing study

Clinical trial • Enrolling • 19 February 2010

The Evaluation of the Impacts of a Doctor – Pharmacist Collaborative Prescribing Model on the Management of Human Immunodeficiency Virus (HIV) Infected Patients
Tags: Accessing HIV care and treatment

PHIIDO - disease progression

Clinical trial • Enrolling • 19 February 2010

A prospective cohort study of individuals with primary Human Immunodefiency Virus (HIV) infection to determine immunological and virological factors related to disease progression.
Tags: pathogenesis

Treating influenza

Clinical trial • Cancelled • 19 February 2010

A Randomized Open Label Study Comparing the Efficacy, Safety, and Tolerability of Oral Administration of Amantadine and Ribavirin With Oseltamivir Versus Oseltamivir to Influenza A Virus Infected Immunocompromised Subjects
Tags: symptoms, illnesses and opportunistic infections

Immune responses to hepatitis B

Clinical trial • Unknown • 19 February 2010

Cellular Immune Responses to Hepatitis B Virus (HBV)- Longitudinal Follow up and Natural History
Tags: hepatitis B

GB Virus C, HIV and HCV

Clinical trial • Reported • 17 February 2010

Associations, Outcomes and Genomics of GB Virus C, Hepatitis C Virus and Human Immunodeficiency Virus Infection
Tags: hepatitis C, hepatotoxicity, liver disorders, symptoms, illnesses and opportunistic infections

'Naive T-cell' study

Clinical trial • Unknown • 17 February 2010

Role of Naive T-Cells in the Pathogenesis of T-Cell Decline and Long Term Persistence of HIV
Tags: newly diagnosed, pathogenesis, primary HIV infection

CMV and interferon

Clinical trial • Concluded • 17 February 2010

Evaluation of Interferon-Gamma Responses to HCMV Infection in HIV Positive Individuals
Tags: CMV, symptoms, illnesses and opportunistic infections

AVX-754

Clinical trial • Concluded • 17 February 2010

A Phase II, Randomised, Double-blind, Dose-ranging Study of AVX754 Versus Lamivudine in Treatment-experienced HIV-1 Infected Patients With the M184V Mutation in Reverse Transcriptase
Tags: drug resistance, NRTI

TROP - low bone mineral density

Clinical trial • No longer enrolling • 22 January 2010

Switch From Tenofovir to Raltegravir for Low Bone Mineral Density
Tags: bone disorders, integrase inhibitor, raltegravir