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Newest Clinical Trials

Recently updated entries from the NAPWA Clinical Trials database.

ATAHC: Australian trial in acute hepatitis C

Clinical trial • Reported • 29 April 2008

Australian Trial in Acute Hepatitis C
Tags: hepatitis C, liver disorders

VERxVE (fast and slow release nevirapine)

Clinical trial • Fully enrolled • 28 March 2008

A Randomised, Double Blind, Double Dummy, Parallel Group, Active Controlled Trial to Evaluate the Antiviral Efficacy of 400 mg QD Nevirapine Extended Release Formulation in Comparison to 200 mg BID Nevirapine Immediate Release in Combination With Truvada? in Antiretroviral Therapy Naive HIV-1 Infect
Tags: liver disorders, optimised background regimens, treatment side effects

'Booster' study

Clinical trial • Not yet started • 3 August 2010

Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of GS-9350-boosted Atazanavir Versus Ritonavir-boosted Atazanavir Each Administered With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults

QUAD

Clinical trial • Enrolling • 21 May 2010

A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Elvitegravir/Emtricitabine/Tenofovir Disoproxil Fumarate/GS-9350 Versus Ritonavir-Boosted Atazanavir Plus Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults

TROP - low bone mineral density

Clinical trial • Enrolling • 22 January 2010

Switch From Tenofovir to Raltegravir for Low Bone Mineral Density
Tags: bone disorders, integrase inhibitor, raltegravir

UK-453, 061

Clinical trial • Enrolling • 24 March 2009

A Study Of Different Doses Of UK-453, 061 Plus Truvada Compared To Efavirenz Plus Truvada In Patients Who Have Not Been Previously Treated For HIV-1
Tags: drug resistance, NNRTI

Second line

Clinical trial • Enrolling • 26 June 2008

A Randomised Open-label Study Comparing the Safety and Efficacy of Ritonavir Boosted Lopinavir and 2-3N(t)RTI Backbone Versus Ritonavir Boosted Lopinavir and Raltegravir in Participants Virologically Failing First-line NNRTI/2N(t)RTI Therapy
Tags: first-line therapy, salvage therapy

ENCORE-1

Clinical trial • Not yet started • 27 June 2008

A Randomised, Double-blind, Placebo-controlled, Clinical Trial to Compare the Safety and Efficacy of Reduced Dose Efavirenz (EFV) With Standard Dose EFV Plus Two Nucleotide Reverse Transcriptase Inhibitors (N(t)RTI) in Antiretroviral-naïve HIV-infected Individuals Over 96 Weeks
Tags: clinical trials

TMC278 (rilpivirine) versus efavirenz (2 trials)

Clinical trial • Concluded • 22 October 2008

A Phase III, Randomized, Double-Blind Trial of TMC278 25mg q.d. Versus Efavirenz 600mg q.d. in Combination With a Background Regimen Containing 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Antiretroviral-Naive HIV-1 Infected Subjects >>>>> AND <<<< A Phase III, Randomized, Double-Blind Trial of TMC278 25 mg q.d. Versus Efavirenz 600mg q.d. in Combination With a Fixed Background Regimen Consisting of Tenofovir Disoproxil Fumarate and Emtricitabine in Antiretroviral-Naive HIV-1 Infected Subjects.

START (Strategic Timing of AntiRetroviral Treatment)

Clinical trial • Enrolling • 9 April 2009

Strategic Timing of AntiRetroviral Treatment (START)
Tags: starting treatments