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Clinical trials database - open trials

Open clinical trials in the NAPWHA database are listed below – the most recently-added entries are shown at the top of the list.

(‘Open’ clinical trials are those listed as enrolling now or not yet started.)

MARCH

Clinical trial • Enrolling • 18 October 2011

A randomised, open-label study to evaluate the efficacy and safety of maraviroc (MVC) as a switch for either nucleoside or nucleotide analogue reverse transcriptase inhibitors (N(t)RTI) or boosted protease inhibitors (PI/r) in HIV-1 infected individuals with stable, well-controlled plasma HIV-RNA while taking their first N(t)RTI + PI/r regimen of combination antiretroviral therapy (cART)

Improving antiretroviral treatment (ART) initiation for people with HIV in Australia

Clinical trial • Enrolling • 12 February 2013

Improving antiretroviral treatment (ART) initiation for people living with HIV in Australia: a realistic and viable approach? Sub-study 3: interviewing people diagnosed with HIV currently not on ART.
Tags: Understanding HIV treatments, living with HIV, starting treatments

SoS - Statin or Switch

Clinical trial • Enrolling • 11 February 2013

Rosuvastatin versus Protease Inhibitor switching for Hypercholesterolaemia in people with HIV.
Tags: cholesterol, clinical trials, lipid disorders, treatment side effects

Opposites Attract

Clinical trial • Enrolling • 11 February 2013

Opposites Attract

ROaR+

Clinical trial • Enrolling • 24 March 2011

Post-prandial Lipid Effects of Raltegravir (RAL) vs Ritonavir-boosted Darunavir (DRV-r) in Anti-retroviral Therapy (ART)-Naive Adults
Tags: heart disease

START (Strategic Timing of AntiRetroviral Treatment)

Clinical trial • Enrolling • 9 April 2009

Strategic Timing of AntiRetroviral Treatment (START)
Tags: starting treatments

BMS-790052 for PLHIV with HCV

Clinical trial • Enrolling • 7 February 2012

A Phase 3, Open Label Study of Safety and Efficacy With BMS-790052 Plus Peg-Interferon Alfa 2a and Ribavirin in Previously Untreated HCV Patients Coinfected With Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV)

CVD risk reduction

Clinical trial • Enrolling • 23 November 2011

Effectiveness of Team Intervention Over 12 Months in Reducing Modifiable CVD Risk Factors on Framingham 10yr Risk Scores Outcomes in HIV-1 Subjects on Antiretroviral Therapy

Pharmacist prescribing study

Clinical trial • Enrolling • 19 February 2010

The Evaluation of the Impacts of a Doctor – Pharmacist Collaborative Prescribing Model on the Management of Human Immunodeficiency Virus (HIV) Infected Patients
Tags: Accessing HIV care and treatment

PHIIDO - disease progression

Clinical trial • Enrolling • 19 February 2010

A prospective cohort study of individuals with primary Human Immunodefiency Virus (HIV) infection to determine immunological and virological factors related to disease progression.
Tags: pathogenesis

Immune responses to hepatitis B

Clinical trial • Unknown • 19 February 2010

Cellular Immune Responses to Hepatitis B Virus (HBV)- Longitudinal Follow up and Natural History
Tags: hepatitis B

'Naive T-cell' study

Clinical trial • Unknown • 17 February 2010

Role of Naive T-Cells in the Pathogenesis of T-Cell Decline and Long Term Persistence of HIV
Tags: newly diagnosed, pathogenesis, primary HIV infection

The Structured Treatment Interruption (STI) Study

Clinical trial • Not yet started • 22 October 2008

A Randomized, Multicenter Trial to Determine Whether Induction Therapy Followed by Treatment Interruption is Superior to Induction Therapy Alone in the Treatment of Primary HIV Infection (PHI): The Structured Treatment Interruption (STI) Study

Predictors of drug hypersensitivity

Clinical trial • Enrolling • 11 May 2007

Predictors of Drug Hypersensitivity in HIV-infected subjects
Tags: hypersensitivity reactions

HIV/HBV coinfection and liver disease

Clinical trial • Enrolling • 11 May 2007

Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV) co-Infection and Liver Disease
Tags: hepatitis B, liver disorders

HIV/HBV coinfection and tenofovir resistance

Clinical trial • Enrolling • 28 March 2008

A surveillance program for the detection of hepatitis B virus (HBV) resistance to tenofovir (TDF) in HIV-HBV co-infected patients
Tags: hepatitis B

HIV/HBV or HIV/HCV coinfection

Clinical trial • Enrolling • 23 April 2008

A Study of Innate Immunity in HIV Positive Patients co-Infected With Hepatitis C or Hepatitis B
Tags: hepatitis B, hepatitis C, innate immunity