Clinical trial • Enrolling • 9 April 2009
Strategic Timing of AntiRetroviral Treatment (START)
Keywords: starting treatments
Clinical trial • No longer enrolling • 8 April 2009
A Phase II multicenter, open-label,
randomized, parallel group, study of
bevirimat in HIV-1 positive patients to evaluate the safety, efficacy, and pharmacokinetics of bevirimat administered as monotherapy for 14 days and as part of an optimized background regimen for
up to 24 weeks.
Clinical trial • No longer enrolling • 8 April 2009
Cardiovascular function with switching from Kivexa to Truvada (or from Abacavir to Tenofovir) in people with Human Immunodeficiency Virus (HIV).
Keywords: heart disease
Clinical trial • Fully enrolled • 8 April 2009
A one-year, open label, extension study of flupirtine for the treatment of painful HIV-sensory neuropathy in patients who have pain inadequately controlled by opioids
Keywords: peripheral neuropathy
Clinical trial • Enrolling • 24 March 2009
A Study Of Different Doses Of UK-453, 061 Plus Truvada Compared To Efavirenz Plus Truvada In Patients Who Have Not Been Previously Treated For HIV-1
Clinical trial • Cancelled • 14 November 2008
A Large, Simple Trial Comparing Two Strategies for Management of Anti-Retroviral Therapy (The SMART Study)
Keywords: SMART, treatment interruption
Clinical trial • Fully enrolled • 13 November 2008
Genomics: A Substudy of a Large, Simple Trial Comparing Two Strategies for Management of Anti-Retroviral Therapy (The SMART Study)
Keywords: genetics, SMART
Clinical trial • No longer enrolling • 10 November 2008
Neurology: A Substudy of a Large, Simple Trial Comparing Two Strategies for Management of Anti-Retroviral Therapy (SMART) to Determine the Impact of the Strategies Upon Central and Peripheral Nervous System Function
Keywords: dementia, peripheral neuropathy
Clinical trial • Enrolling • 22 October 2008
A Multicenter, Randomized, Double-Blind, Double-Dummy, Phase 3 Study of the Safety and Efficacy of Ritonavir-Boosted Elvitegravir (EVG/r) Versus Raltegravir (RAL) Each Administered With a Background Regimen in HIV-1 Infected, Antiretroviral Treatment-Experienced Adults
Clinical trial • Fully enrolled • 22 October 2008
A Phase III, Randomized, Double-Blind Trial of TMC278 25mg q.d. Versus Efavirenz 600mg q.d. in Combination With a Background Regimen Containing 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Antiretroviral-Naive HIV-1 Infected Subjects >>>>> AND <<<< A Phase III, Randomized, Double-Blind Trial of TMC278 25 mg q.d. Versus Efavirenz 600mg q.d. in Combination With a Fixed Background Regimen Consisting of Tenofovir Disoproxil Fumarate and Emtricitabine in Antiretroviral-Naive HIV-1 Infected Subjects.
Clinical trial • Enrolling • 22 October 2008
Impact of HIV Infection and Treatment With Highly Active Antiretroviral Therapy on Reverse Cholesterol Transport
Keywords: heart disease
Clinical trial • Not yet started • 22 October 2008
A Randomized, Multicenter Trial to Determine Whether Induction Therapy Followed by Treatment Interruption is Superior to Induction Therapy Alone in the Treatment of Primary HIV Infection (PHI): The Structured Treatment Interruption (STI) Study
Clinical trial • Not yet started • 26 June 2008
A randomised, open-label study comparing the safety and efficacy of two different combination antiretroviral regimens as second-line therapy for control of HIV infection after first-line regimen failure in resource-rich and -limited settings
Keywords: first-line therapy
Clinical trial • Reported • 23 May 2008
A Randomized Phase II, Double-Blind, Controlled Trial to Evaluate the Safety and Efficacy of Autologous CD34+ Hematopoietic Progenitor Cells Transduced With Placebo or an Anti-HIV-1 Ribozyme (OZ1) in Patients With HIV-1 Infection
Clinical trial • Enrolling • 5 May 2008
A Randomized, Open-Label Trial to Compare the Efficacy, Safety and Tolerability of DRV/Rtv (800mg/100mg) q.d Versus DRV/Rtv (600mg/100mg) b.i.d in Early Treatment-Experienced HIV-1 Infected Subjects.
Keywords: optimised background regimens
