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Clinical trials database

Clinical trials in the NAPWA database are listed below - the most recently-added entries are shown at the top of the list. Click the trial name for more information about that trial.

'Booster' study

Clinical trial • Not yet started • 3 August 2010

Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of GS-9350-boosted Atazanavir Versus Ritonavir-boosted Atazanavir Each Administered With Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults

QUAD

Clinical trial • Enrolling • 21 May 2010

A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of Elvitegravir/Emtricitabine/Tenofovir Disoproxil Fumarate/GS-9350 Versus Ritonavir-Boosted Atazanavir Plus Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults

Pharmacist prescribing study

Clinical trial • Enrolling • 19 February 2010

The Evaluation of the Impacts of a Doctor – Pharmacist Collaborative Prescribing Model on the Management of Human Immunodeficiency Virus (HIV) Infected Patients
Tags: Accessing HIV care and treatment

PHIIDO - disease progression

Clinical trial • Enrolling • 19 February 2010

A prospective cohort study of individuals with primary Human Immunodefiency Virus (HIV) infection to determine immunological and virological factors related to disease progression.
Tags: pathogenesis

Treating influenza

Clinical trial • Enrolling • 19 February 2010

A Randomized Open Label Study Comparing the Efficacy, Safety, and Tolerability of Oral Administration of Amantadine and Ribavirin With Oseltamivir Versus Oseltamivir to Influenza A Virus Infected Immunocompromised Subjects
Tags: symptoms, illnesses and opportunistic infections

Immune responses to hepatitis B

Clinical trial • Unknown • 19 February 2010

Cellular Immune Responses to Hepatitis B Virus (HBV)- Longitudinal Follow up and Natural History
Tags: hepatitis B

GB Virus C, HIV and HCV

Clinical trial • Reported • 17 February 2010

Associations, Outcomes and Genomics of GB Virus C, Hepatitis C Virus and Human Immunodeficiency Virus Infection
Tags: hepatitis C, hepatotoxicity, liver disorders, symptoms, illnesses and opportunistic infections

'Naive T-cell' study

Clinical trial • Unknown • 17 February 2010

Role of Naive T-Cells in the Pathogenesis of T-Cell Decline and Long Term Persistence of HIV
Tags: newly diagnosed, pathogenesis, primary HIV infection

CMV and interferon

Clinical trial • Unknown • 17 February 2010

Evaluation of Interferon-Gamma Responses to HCMV Infection in HIV Positive Individuals
Tags: CMV, symptoms, illnesses and opportunistic infections

AVX-754

Clinical trial • Concluded • 17 February 2010

A Phase II, Randomised, Double-blind, Dose-ranging Study of AVX754 Versus Lamivudine in Treatment-experienced HIV-1 Infected Patients With the M184V Mutation in Reverse Transcriptase
Tags: drug resistance, NRTI

TROP - low bone mineral density

Clinical trial • Enrolling • 22 January 2010

Switch From Tenofovir to Raltegravir for Low Bone Mineral Density
Tags: bone disorders, integrase inhibitor, raltegravir

SPARTA

Clinical trial • No longer enrolling • 21 August 2009

A Randomised, Open-Label, Cross-Over Study to Examine the Pharmacokinetics and Short-Term Safety and Efficacy of Two Dosing Strategies of Raltegravir Plus Atazanavir in HIV-Infected Patients
Tags: atazanavir, first-line therapy, raltegravir

START (Strategic Timing of AntiRetroviral Treatment)

Clinical trial • Enrolling • 9 April 2009

Strategic Timing of AntiRetroviral Treatment (START)
Tags: starting treatments

Bevirimat monotherapy

Clinical trial • No longer enrolling • 8 April 2009

A Phase II multicenter, open-label, randomized, parallel group, study of bevirimat (MPC-4326) in HIV-1 positive patients to evaluate the safety, efficacy, and pharmacokinetics of bevirimat administered as monotherapy for 14 days and as part of an optimized background regimen for up to 72 weeks.
Tags: Bevirimat

SKiT (abacavir to tenofovir)

Clinical trial • No longer enrolling • 8 April 2009

Cardiovascular function with switching from Kivexa to Truvada (or from Abacavir to Tenofovir) in people with Human Immunodeficiency Virus (HIV).
Tags: heart disease