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UK-453, 061

UK-453, 061 is a second generation NNRTI (or non-nuke).

In Phase IA clinical trial designed to establish whether an experimental drug is safe for humans to take. Phase I studies determine the metabolism and pharmacologic actions of drugs in humans, the side effects associated with increasing doses, and look for early evidence of effectiveness; these studies may include either people with HIV, HIV-negative volunteers, or both trials it proved to be effective against mutations of HIV which were resistantHIV which has mutated and is less susceptible to the effects of one or more anti-HIV drugs is said to be resistant. to first generation NNRTIs, like nevirapine and efavirenz.

Generic name: UK-453, 061
Drug class:non-nucleoside
Availability in Australia:
  • Not available on the Pharmaceutical Benefits Scheme (PBS).
  • This drug may be available through clinical trials in Australia.

Like most anti-HIV drugs, UK-453, 061 must be taken in combination with other drugs to be completely effective. Commonly, UK-453, 061 is combined with two nucleoside (NRTI) drugs, although other combinations are sometimes used. Your doctor will advise you on the right combination of drugs to suit your circumstances.

Side effects

All drugs can produce side effects in some people. These may be mild, moderate or severe, so you should be aware of potential side effects before starting any drug, and speak to your doctor if you experience side effects that concern you.

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    The table below shows all the clinical trials in the database with the keyword UK-453,061.

    Short titleStatus
    UK-453, 061 Enrolling
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    This Treatments database entry was first published on 1 June 2010.

    While the content of this treatments database entry was checked for accuracy at the time of publication, NAPWA recommends checking to determine whether the information is the most up-to-date available, especially when making decisions which may affect your health.

    This article may contain medical information. NAPWA makes every reasonable effort to ensure the information on this website is accurate, reliable and up-to-date, including obtaining technical reviews by medically-qualified reviewers, however the authors of information on this website are not qualified to give medical advice, except where explicitly stated.

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