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New non-nuke approved

Positive Living article • Adrian Ogier • 5 June 2009

A new Non-Nucleoside Reverse Transcriptase InhibitorA type of anti-HIV drug which works by interfering with an enzyme, reverse transcriptase, that HIV needs to reproduce. – etravirine – will be listed on the Pharmaceutical Benefits Scheme[Pharmaceutical Benefits Scheme] The federal government program which subsidises medication costs in Australia. Anti-HIV drugs are part of a special part of the PBS called Section 100 (S100) which is used for expensive, highly specialised drugs. (PBS) from July 1.

Non-nukes form an important backbone of many people’s drug regimens however resistance to the two others currently prescribed – nevirapine and efavirenz – is common. Fortunately, etravirine has proved effective in many people who are resistantHIV which has mutated and is less susceptible to the effects of one or more anti-HIV drugs is said to be resistant. to these drugs.

Its addition to the antiretroviralsA medication or other substance which is active against retroviruses such as HIV. currently available in Australia will benefit many of the more treatment-experienced. Its indication for use targets those who have had at least three treatment combinations fail in their therapy history.

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From Positive Living

This article was first published in the June 2009 issue of Positive Living — more than one year ago.

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