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Treating HIV

ViiV Announces Halt to Lersivirine Development

HIV Media Digest - 8 February 2013 - 9:10am
On February 5, 2013, ViiV Healthcare announced that the company has decided to stop the development program investigating its experimental non-nucleoside reverse transcriptase inhibitor (NNRTI) lersivirine.

Pregnancy does not increase risk of nevirapine side-effects

Aidsmap - 7 February 2013 - 6:10pm
Pregnancy does not increase the risk of nevirapine (Viramune) associated side-effects, according to the results of a systematic review and meta-analysis published in the online edition of AIDS. Investigators found that incidence of liver and skin toxicities – the major side-effects of the drug  – were high, but no higher than the rate observed in the

Tenofovir impairs enzyme that stops cells ageing

Aidsmap - 31 January 2013 - 8:00pm
A team of Australian researchers has found that tenofovir and, to a lesser extent, other drugs from the nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) class, impairs an enzyme that slows down or stops ageing processes in immune cells in the test tube. They also found that, in people living with HIV, a marker of cell age called
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HIV Clinical Trials update